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Triprolidine HCl Actifed is a registered trademark for a combination antihistamine and nasal decongestant medication used for cold and allergy symptoms. Developed in 1958 by Burroughs Wellcome & Company (now part of GlaxoSmithKline),[1] the product was later acquired by Pfizer, and was most recently sold by Johnson & Johnson. The formula was changed in 2006 due to a change in the legal environment in the US. In the US, the product has been limited to certain stores.
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